mitochondria

SARS-CoV-2 structural proteins trigger periodontal fibrosis

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In a recent study posted to the bioRxiv* preprint server, researchers examined the pathological impacts of the structural components of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) on human periodontal cells and tissue to understand the association between coronavirus disease 2019 (COVID-19) and deteriorating oral health. Study: SARS-CoV-2 causes periodontal fibrosis by deregulating mitochondrial β-oxidation. … Read more

SARS-CoV-2 open reading frame 3c protein found to be targeted selectively to mitochondria

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In a recent study posted to the bioRxiv* preprint server, researchers presented a functional analysis of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) open reading frame 3c (ORF3c) protein. Study: The SARS-CoV-2 protein ORF3c is a mitochondrial modulator of innate immunity. Image Credit: Corona Borealis Studio/Shutterstock Background The genome of SARS-CoV-2 encodes a wide … Read more

A “door” into the mitochondrial membrane | MIT News

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Mitochondria — the organelles responsible for energy production in human cells — were once free-living organisms that found their way into early eukaryotic cells over a billion years ago. Since then, they have merged seamlessly with their hosts in a classic example of symbiotic evolution, and now rely on many proteins made in their host … Read more