in vivo

Chitin-immobilized nanobodies for SARS-CoV-2 detection

by

In a recent study posted to bioRxiv*, researchers demonstrated a novel strategy to detect severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) using chitin-immobilized nanobodies. Study: Efficient SARS-CoV-2 detection utilizing chitin-immobilized nanobodies synthesized in Ustilago maydis. Image Credit: CROCOTHERY/Shutterstock Background Shark and Camelidae-derived nanobodies are emerging alternatives to traditional antibodies. Nanobodies bind to ligands at the … Read more

emerging technologies are capable of unlocking the promise of biologically targeted mRNA therapeutics

by

In a recent article published in Nature Biotechnologyresearchers reviewed technology advancements that will unlock the promise of biologically targeted messenger ribonucleic acid (mRNA) therapeutics beyond vaccines. Study: Unlocking the promise of mRNA therapeutics. Image Credit: nobeastsofierce/Shutterstock Background The first part of the review focused on the design and purification of the mRNA cargos, including novel … Read more

Fermented dairy products can improve gut mucosal immunity

by

In a recent study published in the journal Immunology Lettersresearchers assessed the role of fermented dairy products and dairy starters in modulating gut mucosal immunity. The gut microbiota significantly influences the modulation of mucosal immunity and the role of the intestinal barrier. Accordingly, dysbiosis is linked to the breakdown of mucosal immunological homeostasis, which results … Read more

Researchers find new way to deliver a protein quickly, effectively and briefly to the brain

by

Many diseases have at their origin a protein that does not function properly. Now, a multidisciplinary research team with Texas A&M AgriLife and Texas A&M University has found a way to deliver a protein quickly, effectively and briefly to the brain, with therapeutic and scientific implications. Potential uses for the method in the future could … Read more