Novel mRNA-lipid nanoparticle vaccine encoding four mpox virus surface proteins generates robust immune responses against orthopoxviruses

In a recent study posted to the bioRxiv* preprint server, researchers described a messenger ribonucleic acid (mRNA)-lipid nanoparticle mpox vaccine encoding four conserved mpox virus surface proteins which induced mpox virus-specific immunity and elicited heterologous protection when challenged with lethal vaccinia virus. Study: A monkeypox mRNA-lipid nanoparticle vaccine targeting virus binding, entry, and transmission drives … Read more

Researchers generate a remodeled live-attenuated measles vaccine capable of driving nAb responses against SARS-CoV-2 spike protein

In a recent study posted to bioRxiv*, researchers developed a measles virus (MeV)-vectored vaccine capable of inducing high neutralizing antibody (nAb) responses against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Study: Surface-modified measles vaccines encoding oligomeric, fusion-stabilized SARS-CoV-2 spike glycoproteins bypass measles seropositivity, boosting neutralizing antibody responses to omicron and historical variants. Image Credit: Kateryna … Read more

writer; know what juice diet is that he follows; is it healthy?

Kamal Hasan is following a strict juice diet while sitting for prosthetic makeup during the filming of Indian 2, film’s writer has revealed New Delhi: Kamal Hasan is following a strict juice diet to maintain his looks for the upcoming film Indian2the film’s writer has revealed. Screenwriter B. Jeyamohan revealed that the actor had to … Read more

writer; know what juice diet is that he follows; is it healthy?

Kamal Hasan is following a strict juice diet while sitting for prosthetic makeup during the filming of Indian 2, film’s writer has revealed New Delhi: Kamal Hasan is following a strict juice diet to maintain his looks for the upcoming film Indian2the film’s writer has revealed. Screenwriter B. Jeyamohan revealed that the actor had to … Read more

The frequency, magnitude, and longevity of natural antibody responses against nine P. vivax vaccine candidate proteins

Malaria is a significant public health threat, causing about 241 million cases worldwide in 2020. Although Plasmodium falciparum is reported to be the most common malaria parasite in Africa, P. vivax is the predominant parasite in most countries in America and Asia Pacific. Critical illnessescaused by P. vivax are no more considered rare events. Study: … Read more

Study shows how HIV permanently alters immune cells

Though antiretroviral therapy has made HIV a manageable disease, people living with HIV often suffer from chronic inflammation. This can put them at an increased risk of developing comorbidities such as cardiovascular disease and neurocognitive dysfunction, affecting the longevity and quality of their lives. Now, a new study in Cell Reports explains why chronic inflammation … Read more

Study shows how HIV permanently alters immune cells

Though antiretroviral therapy has made HIV a manageable disease, people living with HIV often suffer from chronic inflammation. This can put them at an increased risk of developing comorbidities such as cardiovascular disease and neurocognitive dysfunction, affecting the longevity and quality of their lives. Now, a new study in Cell Reports explains why chronic inflammation … Read more

The Superior Protein launches ‘GRD Bix’ in 4 flavors for general health, well-being, and immunity

ANI | Updated: Nov 11, 2022 16:52 IST Mumbai (Maharashtra) [India], November 11 (ANI/ATK): GRD- The Superior Protein, from the house of Zydus Nutriva, now offers ‘GRD Bix’ – a nutritional supplement in the form of Protein Diskettes. Available in four delicious flavours, Chocolate, Cardamom, Vanilla, and Milk flavour, the diskettes are formulated with protein, … Read more

emerging technologies are capable of unlocking the promise of biologically targeted mRNA therapeutics

In a recent article published in Nature Biotechnologyresearchers reviewed technology advancements that will unlock the promise of biologically targeted messenger ribonucleic acid (mRNA) therapeutics beyond vaccines. Study: Unlocking the promise of mRNA therapeutics. Image Credit: nobeastsofierce/Shutterstock Background The first part of the review focused on the design and purification of the mRNA cargos, including novel … Read more

Fermented dairy products can improve gut mucosal immunity

In a recent study published in the journal Immunology Lettersresearchers assessed the role of fermented dairy products and dairy starters in modulating gut mucosal immunity. The gut microbiota significantly influences the modulation of mucosal immunity and the role of the intestinal barrier. Accordingly, dysbiosis is linked to the breakdown of mucosal immunological homeostasis, which results … Read more