Researchers discover a protein linked with the onset of anthracycline-associated cardiac toxicity

Anthracyclines are a class of chemotherapies effective in treating many forms of cancer, including leukemias, lymphomas and breast cancer. Anthracyclines -; such as doxorubicin, frequently used against breast cancer -; kill cancer cells by damaging their DNA. However, these effective chemotherapies also cause toxic heart effects in about ten percent of patients that can eventually … Read more

Lower frequency of dietary salt associated with reduced risk of heart disease

Adding additional salt to foods at a lower frequency is associated with a reduced risk of heart disease, heart failure and ischemic heart disease, according to a new study published today in the Journal of the American College of Cardiology. Even among those following a DASH-style diet, behavioral interventions to lessen salt consumption could further … Read more

Iron buildup following a heart attack may be a cause

Share on PinterestIn a new study, researchers found that iron deposits following heart attack lead to the formation of fatty tissue, which causes chronic heart failure in half of survivors. Naz Kay/EyeEm/Getty Images A new study used animal models to investigate why 50% of people develop chronic heart failure after experiencing a heart attack. Researchers … Read more

Novel gene editing therapy reduces circulating TTR protein levels in patients with ATTR amyloid cardiomyopathy

A single IV infusion of NTLA-2001, a novel CRISPR/Cas9-based gene editing therapy, significantly reduced circulating transthyretin (TTR) protein levels in patients with ATTR amyloid fatal cardiomyopathy, a progressive and cause of heart failure, according to late-breaking research presented today at the American Heart Association’s Scientific Sessions 2022. The meeting, held in person in Chicago and … Read more

High immune protein levels predict both heart failure and death

For years, cardiologists have zeroed in on a hormone called BNP as a gold standard to determine if patients with heart failure are at risk of severe illness or death. It’s released by the heart in response to when the cardiac tissue stretches due to pressure. While the B-type natriuretic peptide, or BNP, is a … Read more