Precision fermentation-fueled startup Helaina to expand protein offerings beyond babies

Helena is the company behind the advanced infant formula with proteins identical to those found in breast milk. The New York City-based company was founded in 2019 by food scientist Laura Katz​, who wanted to advance infant nutrition by recreating the functional components of breast milk. Now Katz is ready to expand the use case … Read more

Pocket feature in SARS-CoV-2 spike protein is present in all deadly coronaviruses, study reveals

Scientists have discovered why some coronaviruses are more likely to cause severe disease, which has remained a mystery until now. Researchers of the University of Bristol-led study, published in Science advances today [23 November], say their findings could lead to the development of a pan-coronavirus treatment to defeat all coronaviruses-; from the 2002 SARS-CoV outbreak … Read more

Structure-directed mutagenesis produces thermostable SARS-CoV-2 spike protein trimers with potential vaccine booster applications

In a recent study posted to the bioRxiv* preprint server, a team of researchers investigated the change in the stability, antigenicity, and protein expression of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein trimer using structure-directed mutagenesis to alter a cavity in the core of the spike protein. Study: Enhanced stability of the … Read more

Study indicates that the major determinants of SARS-CoV-2 pathogenicity reside outside of the spike protein

In a recent study posted to the bioRxiv* server, researchers at Boston University made a chimeric recombinant severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) encoding the spike(S) glycoprotein gene of Omicron in the backbone of an ancestral SARS-CoV-2 isolate. Study: Role of spike in the pathogenic and antigenic behavior of SARS-CoV-2 BA.1 Omicron. Image Credit: … Read more